MEDUSA: Prediction of Protein Flexibility from Sequence
نویسندگان
چکیده
منابع مشابه
Prediction of protein flexibility from geometrical constraints
quency motions, the so called "essential" degrees of freedom [1, 2], which typically appear in timescales of nanoseconds to microseconds and play important roles in signalling, activation and enzyme function. Despite the rapid growth of computer power these timescales are not accessible with current molecular dynamic simulations systems. The CONCOORD system attempts to alleviate this sampling p...
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Investigation of protein gene function is a central question in molecular biology, biochemistry, and genetics. Because genes evolved from the same ancestral gene retain similarity in their function in most cases, finding known genes which have sufficient sequence similarity is a powerful way for predicting function. In this chapter we review computational techniques and resources for gene funct...
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ژورنال
عنوان ژورنال: Journal of Molecular Biology
سال: 2021
ISSN: 0022-2836
DOI: 10.1016/j.jmb.2021.166882